NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial

BE0000081ProteinHumansNDUFA10

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. It is acted on by 1 drug in DrugBank.

Gene name
NDUFA10
UniProtKB entry
O95299Swiss-Prot
Cellular location
Mitochondrion matrix
Residues / weight
355 residues · 40,750 Da
Also known as
CI-42kD · Complex I-42kD · NADH-ubiquinone oxidoreductase 42 kDa subunit

Resolves to

Protein
UniProtO95299UniProt nameNDUAA_HUMAN
Gene
HGNCHGNC:7684NCBI Gene4705GenBank4191348GeneCardsNDUFA10
Pharmacology
KEGGhsa:4705
Structure
PDB5XTCPDB5XTDPDB5XTH
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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9+ReferencesStructured and connected to the statements they support
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Which approved drugs act on NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial, how selective are they, and which programs against it are still in active trials?

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