Histidine ammonia-lyase

BE0000086ProteinHumansHAL

Catalyzes the first reaction in histidine catabolism, the non-oxidative deamination of L-histidine to trans-urocanic. It is acted on by 2 drugs in DrugBank.

Gene name
HAL
UniProtKB entry
P42357Swiss-Prot
Residues / weight
657 residues · 72,697 Da
Also known as
4.3.1.3 · HIS · Histidase

Resolves to

Protein
UniProtP42357UniProt nameHUTH_HUMAN
Gene
HGNCHGNC:4806NCBI Gene3034GenBank451210GeneCardsHAL
Pharmacology
KEGGhsa:3034
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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15+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Histidine ammonia-lyase, how selective are they, and which programs against it are still in active trials?

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