Diamine acetyltransferase 1

BE0000111ProteinHumansSAT1

Enzyme which catalyzes the acetylation of polyamines (PubMed:15283699, PubMed:16455797, PubMed:17516632). It is acted on by 5 drugs in DrugBank.

Gene name
SAT1
UniProtKB entry
P21673Swiss-Prot
Cellular location
Cytoplasm, cytosol
Residues / weight
171 residues · 20,024 Da
Also known as
2.3.1.57 · Polyamine N-acetyltransferase 1 · Putrescine acetyltransferase · SAT · Spermidine/spermine N(1)-acetyltransferase 1

Resolves to

Protein
UniProtP21673UniProt nameSAT1_HUMAN
Gene
HGNCHGNC:10540NCBI Gene6303GenBank338392GeneCardsSAT1
Pharmacology
KEGGhsa:6303
Structure
PDB2B3UPDB2B3VPDB2B4B
Drugs

What you can answer from here — as of September 07, 2019

5DrugsApproved to experimental, with action, bond type and pharmacological action
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2Metabolic reactionsDrug transformations it catalyses, substrate to product
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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30+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Diamine acetyltransferase 1, how selective are they, and which programs against it are still in active trials?

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