Potassium channel subfamily K member 1

BE0000154ProteinHumansKCNK1

Ion channel that contributes to passive transmembrane potassium transport and to the regulation of the resting membrane potential in brain astrocytes, but also in kidney and in other tissues (PubMed:15820677, PubMed:21653227). It is acted on by 3 drugs in DrugBank.

Gene name
KCNK1
UniProtKB entry
O00180Swiss-Prot
Cellular location
Cell membrane
Residues / weight
336 residues · 38,143 Da
Also known as
HOHO1 · Inward rectifying potassium channel protein TWIK-1 · KCNO1 · Potassium channel K2P1 · Potassium channel KCNO1

Resolves to

Protein
UniProtO00180UniProt nameKCNK1_HUMAN
Gene
HGNCHGNC:6272NCBI Gene3775GenBank1086491GeneCardsKCNK1
Pharmacology
IUPHAR/GtoPdb513KEGGhsa:3775
Structure
PDB3UKM
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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15GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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27+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Potassium channel subfamily K member 1, how selective are they, and which programs against it are still in active trials?

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