High affinity cationic amino acid transporter 1

BE0000212ProteinHumansSLC7A1

High-affinity, low capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine) in non-hepatic tissues. It is acted on by 4 drugs in DrugBank.

Gene name
SLC7A1
UniProtKB entry
P30825Swiss-Prot
Cellular location
Cell membrane
Residues / weight
629 residues · 67,638 Da
Also known as
ATRC1 · CAT-1 · CAT1 · Ecotropic retroviral leukemia receptor homolog · Ecotropic retrovirus receptor homolog

Resolves to

Protein
UniProtP30825UniProt nameCTR1_HUMAN
Gene
HGNCHGNC:11057NCBI Gene6541GenBank36161GeneCardsSLC7A1
Pharmacology
KEGGhsa:6541
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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19GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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19+ReferencesStructured and connected to the statements they support
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Which approved drugs act on High affinity cationic amino acid transporter 1, how selective are they, and which programs against it are still in active trials?

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