Histo-blood group ABO system transferase

BE0000214ProteinHumansABO

This protein is the basis of the ABO blood group system. It is acted on by 13 drugs in DrugBank.

Gene name
ABO
UniProtKB entry
P16442Swiss-Prot
Cellular location
Golgi apparatus, Golgi stack membrane
Residues / weight
354 residues · 40,934 Da
Also known as
A transferase · B transferase · Fucosylglycoprotein 3-alpha-galactosyltransferase · Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase · Glycoprotein-fucosylgalactoside alpha-galactosyltransferase

Resolves to

Protein
UniProtP16442UniProt nameBGAT_HUMAN
Gene
HGNCHGNC:79NCBI Gene28GenBank340078GeneCardsABO
Structure
PDB1LZ0PDB1LZ7PDB1LZI
Drugs

What you can answer from here — as of September 07, 2019

13DrugsApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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33+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Histo-blood group ABO system transferase, and which indications are they being tested in?

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