Adrenodoxin, mitochondrial

BE0000242ProteinHumansFDX1

Essential for the synthesis of various steroid hormones (PubMed:20547883, PubMed:21636783). It is acted on by 1 drug in DrugBank.

Gene name
FDX1
UniProtKB entry
P10109Swiss-Prot
Cellular location
Mitochondrion matrix
Residues / weight
184 residues · 19,392 Da
Also known as
Adrenal ferredoxin · ADX · Ferredoxin-1 · Hepatoredoxin

Resolves to

Protein
UniProtP10109UniProt nameADX_HUMAN
Gene
HGNCHGNC:3638NCBI Gene2230GenBank557734GeneCardsFDX1
Pharmacology
KEGGhsa:2230
Structure
PDB3N9YPDB3N9ZPDB3NA0
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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16+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Adrenodoxin, mitochondrial, how selective are they, and which programs against it are still in active trials?

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