NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10

BE0000245ProteinHumansNDUFB10

Accessory subunit that is involved in the functional assembly of the mitochondrial respiratory chain complex I. It is acted on by 1 drug in DrugBank.

Gene name
NDUFB10
UniProtKB entry
O96000Swiss-Prot
Cellular location
Mitochondrion inner membrane
Residues / weight
172 residues · 20,777 Da
Also known as
CI-PDSW · Complex I-PDSW · NADH-ubiquinone oxidoreductase PDSW subunit

Resolves to

Protein
UniProtO96000UniProt nameNDUBA_HUMAN
Gene
HGNCHGNC:7696NCBI Gene4716GenBank4164442GeneCardsNDUFB10
Pharmacology
KEGGhsa:4716
Structure
PDB5XTCPDB5XTDPDB5XTH
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which approved drugs act on NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10, how selective are they, and which programs against it are still in active trials?

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