Mitochondrial ornithine transporter 2

BE0000258ProteinHumansSLC25A2

Mitochondrial transporter of the positively charged amino acids ornithine, lysine and arginine, and the neutral amino acid citrulline (PubMed:12807890). It is acted on by 1 drug in DrugBank.

Gene name
SLC25A2
UniProtKB entry
Q9BXI2Swiss-Prot
Cellular location
Mitochondrion membrane
Residues / weight
301 residues · 32,580 Da
Also known as
ORC2 · ORNT2 · Solute carrier family 25 member 2

Resolves to

Protein
UniProtQ9BXI2UniProt nameORNT2_HUMAN
Gene
HGNCHGNC:22921NCBI Gene83884GenBank13445628GeneCardsSLC25A2
Pharmacology
KEGGhsa:83884
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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10GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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6+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Mitochondrial ornithine transporter 2, how selective are they, and which programs against it are still in active trials?

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