Thialysine N-epsilon-acetyltransferase

BE0000275ProteinHumansSAT2

Catalyzes the N-acetylation of the amino acid thialysine (S-(2-aminoethyl)-L-cysteine), a L-lysine analog with the 4-methylene group substituted with a sulfur (PubMed:15283699). It is acted on by 1 drug in DrugBank.

Gene name
SAT2
UniProtKB entry
Q96F10Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
170 residues · 19,155 Da
Also known as
2.3.1.- · Diamine acetyltransferase 2 · Spermidine/spermine N(1)-acetyltransferase 2 · SSAT-2 · SSAT2

Resolves to

Protein
UniProtQ96F10UniProt nameSAT2_HUMAN
Gene
HGNCHGNC:23160NCBI Gene112483GenBank19070527GeneCardsSAT2
Pharmacology
KEGGhsa:112483
Structure
PDB2BEIPDB2Q4V
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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9+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Thialysine N-epsilon-acetyltransferase, and which indications are they being tested in?

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