Sigma non-opioid intracellular receptor 1

BE0000290ProteinHumansSIGMAR1

Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. It is acted on by 1 drug in DrugBank.

Gene name
SIGMAR1
UniProtKB entry
Q5T1J1TrEMBL
Residues / weight
134 residues · 14,853 Da
Also known as
HCG20471, isoform CRA_c · Sigma 1-type opioid receptor

Resolves to

Protein
UniProtQ5T1J1UniProt nameQ5T1J1_HUMAN
Gene
HGNCHGNC:8157GenBank123231939
Drugs

What you can answer from here — as of May 03, 2025

1DrugApproved to experimental, with action, bond type and pharmacological action
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1Pfam domainDomain architecture mapped to Pfam families and clans
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5+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Sigma non-opioid intracellular receptor 1, and which indications are they being tested in?

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