Secretin receptor

BE0000318ProteinHumansSCTR

G protein-coupled receptor activated by secretin (SCT), which is involved in different processes such as regulation of the pH of the duodenal content, food intake and water homeostasis (PubMed:25332973, PubMed:32811827, PubMed:33008599, PubMed:7612008). It is acted on by 2 drugs in DrugBank.

Gene name
SCTR
UniProtKB entry
P47872Swiss-Prot
Cellular location
Cell membrane
Residues / weight
440 residues · 50,206 Da
Also known as
SCT-R · SECR

Resolves to

Protein
UniProtP47872UniProt nameSCTR_HUMAN
Gene
HGNCHGNC:10608NCBI Gene6344GenBank662796GeneCardsSCTR
Pharmacology
IUPHAR/GtoPdb252KEGGhsa:6344
Structure
PDB6WI9PDB6WZGPDB7D3S
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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10GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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9+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Secretin receptor, how selective are they, and which programs against it are still in active trials?

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