Cytochrome c oxidase hypoxia associated subunit FA4L2

BE0000319ProteinHumansCOXFA4L2

Mitochondrial protein that plays a regulatory role in cellular metabolism, particularly under hypoxic conditions (PubMed:22100406). It is acted on by 1 drug in DrugBank.

Gene name
COXFA4L2
UniProtKB entry
Q9NRX3Swiss-Prot
Cellular location
Mitochondrion inner membrane
Residues / weight
87 residues · 9,966 Da
Also known as
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 · NADH-ubiquinone oxidoreductase MLRQ subunit homolog · NDUFA4L2 · NUOMS

Resolves to

Protein
UniProtQ9NRX3UniProt nameCX4L2_HUMAN
Gene
HGNCHGNC:29836NCBI Gene56901GenBank8895095GeneCardsCOXFA4L2
Pharmacology
KEGGhsa:56901
Drugs

What you can answer from here — as of June 05, 2026

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
1GO termFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
4+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Cytochrome c oxidase hypoxia associated subunit FA4L2, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In