NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1

BE0000338ProteinHumansNDUFB1

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed not to be involved in catalysis. It is acted on by 1 drug in DrugBank.

Gene name
NDUFB1
UniProtKB entry
O75438Swiss-Prot
Cellular location
Mitochondrion inner membrane
Residues / weight
58 residues · 6,961 Da
Also known as
CI-MNLL · Complex I-MNLL · NADH-ubiquinone oxidoreductase MNLL subunit

Resolves to

Protein
UniProtO75438UniProt nameNDUB1_HUMAN
Gene
HGNCHGNC:7695NCBI Gene4707GenBank5326820GeneCardsNDUFB1
Pharmacology
KEGGhsa:4707
Structure
PDB5XTCPDB5XTDPDB5XTH
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which approved drugs act on NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1, how selective are they, and which programs against it are still in active trials?

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