Calcineurin subunit B type 1

BE0000358ProteinHumansPPP3R1

Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. It is acted on by 2 drugs in DrugBank.

Gene name
PPP3R1
UniProtKB entry
P63098Swiss-Prot
Cellular location
Cytoplasm, cytosol
Residues / weight
170 residues · 19,300 Da
Also known as
CNA2 · CNB · Protein phosphatase 2B regulatory subunit 1 · Protein phosphatase 3 regulatory subunit B alpha isoform 1

Resolves to

Protein
UniProtP63098UniProt nameCANB1_HUMAN
Gene
HGNCHGNC:9317NCBI Gene5534GenBank180705GeneCardsPPP3R1
Pharmacology
KEGGhsa:5534
Structure
PDB1AUIPDB1M63PDB1MF8
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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9GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Calcineurin subunit B type 1, how selective are they, and which programs against it are still in active trials?

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