Monocarboxylate transporter 3

BE0000361ProteinHumansSLC16A8

Probable retinal pigment epithelium (RPE)-specific proton-coupled L-lactate transporter (By similarity). It is acted on by 1 drug in DrugBank.

Gene name
SLC16A8
UniProtKB entry
O95907Swiss-Prot
Cellular location
Basolateral cell membrane
Residues / weight
504 residues · 52,318 Da
Also known as
MCT 3 · MCT3 · Solute carrier family 16 member 8

Resolves to

Protein
UniProtO95907UniProt nameMOT3_HUMAN
Gene
HGNCHGNC:16270NCBI Gene23539GenBank6103363GeneCardsSLC16A8
Pharmacology
KEGGhsa:23539
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Monocarboxylate transporter 3, how selective are they, and which programs against it are still in active trials?

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