NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7

BE0000401ProteinHumansNDUFA7

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. It is acted on by 1 drug in DrugBank.

Gene name
NDUFA7
UniProtKB entry
O95182Swiss-Prot
Cellular location
Mitochondrion inner membrane
Residues / weight
113 residues · 12,551 Da
Also known as
CI-B14.5a · Complex I-B14.5a · NADH-ubiquinone oxidoreductase subunit B14.5a

Resolves to

Protein
UniProtO95182UniProt nameNDUA7_HUMAN
Gene
HGNCHGNC:7691NCBI Gene4701GenBank4164452GeneCardsNDUFA7
Pharmacology
KEGGhsa:4701
Structure
PDB5XTBPDB5XTDPDB5XTH
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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9+ReferencesStructured and connected to the statements they support
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Which approved drugs act on NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7, how selective are they, and which programs against it are still in active trials?

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