Aldehyde dehydrogenase family 3 member B1

BE0000446ProteinHumansALDH3B1

Oxidizes medium and long chain saturated and unsaturated fatty aldehydes generated in the plasma membrane into non-toxic fatty acids (PubMed:17382292, PubMed:23721920). It is acted on by 1 drug in DrugBank.

Gene name
ALDH3B1
UniProtKB entry
P43353Swiss-Prot
Cellular location
Cell membrane
Residues / weight
468 residues · 51,839 Da
Also known as
1.2.1.28 · 1.2.1.5 · 1.2.1.7 · Aldehyde dehydrogenase 7 · ALDH7

Resolves to

Protein
UniProtP43353UniProt nameAL3B1_HUMAN
Gene
HGNCHGNC:410NCBI Gene221GenBank601780GeneCardsALDH3B1
Pharmacology
KEGGhsa:221
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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1Metabolic reactionDrug transformations it catalyses, substrate to product
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9GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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8+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Aldehyde dehydrogenase family 3 member B1, how selective are they, and which programs against it are still in active trials?

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