NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5

BE0000473ProteinHumansNDUFA5

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. It is acted on by 1 drug in DrugBank.

Gene name
NDUFA5
UniProtKB entry
Q16718Swiss-Prot
Cellular location
Mitochondrion inner membrane
Residues / weight
116 residues · 13,459 Da
Also known as
CI-13kD-B · Complex I subunit B13 · Complex I-13kD-B · NADH-ubiquinone oxidoreductase 13 kDa-B subunit

Resolves to

Protein
UniProtQ16718UniProt nameNDUA5_HUMAN
Gene
HGNCHGNC:7688NCBI Gene4698GenBank1373173GeneCardsNDUFA5
Pharmacology
KEGGhsa:4698
Structure
PDB5XTBPDB5XTDPDB5XTH
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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14+ReferencesStructured and connected to the statements they support
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Which approved drugs act on NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5, how selective are they, and which programs against it are still in active trials?

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