Aminoacylase-1

BE0000481ProteinHumansACY1

Aminoacylase involved in the hydrolysis of N-acetylated and N-formylated amino acids. It is acted on by 3 drugs in DrugBank.

Gene name
ACY1
UniProtKB entry
Q03154Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
408 residues · 45,885 Da
Also known as
3.5.1.14 · ACY-1 · N-acyl-L-amino-acid amidohydrolase

Resolves to

Protein
UniProtQ03154UniProt nameACY1_HUMAN
Gene
HGNCHGNC:177NCBI Gene95GenBank178071GeneCardsACY1
Pharmacology
KEGGhsa:95
Structure
PDB1Q7L
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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1Metabolic reactionDrug transformations it catalyses, substrate to product
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3GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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17+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Aminoacylase-1, how selective are they, and which programs against it are still in active trials?

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