Thymidine kinase

BE0000514ProteinTK

Catalyzes the transfer of the gamma-phospho group of ATP to thymidine to generate dTMP in the salvage pathway of pyrimidine synthesis. It is acted on by 4 drugs in DrugBank.

Gene name
TK
UniProtKB entry
P06478Swiss-Prot
Residues / weight
376 residues · 40,912 Da
Also known as
2.7.1.21 · UL23

Resolves to

Protein
UniProtP06478UniProt nameKITH_HHV1C
Gene
GenBank330210
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
2Metabolic reactionsDrug transformations it catalyses, substrate to product
Sign in
4GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
11+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Thymidine kinase, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In