Melatonin receptor type 1A

BE0000515ProteinHumansMTNR1A

High affinity receptor for melatonin. It is acted on by 10 drugs in DrugBank.

Gene name
MTNR1A
UniProtKB entry
P48039Swiss-Prot
Cellular location
Cell membrane
Residues / weight
350 residues · 39,374 Da
Also known as
Mel-1A-R · Mel1a receptor

Resolves to

Protein
UniProtP48039UniProt nameMTR1A_HUMAN
Gene
HGNCHGNC:7463NCBI Gene4543GenBank602130GeneCardsMTNR1A
Pharmacology
IUPHAR/GtoPdb287KEGGhsa:4543
Structure
PDB6ME2PDB6ME3PDB6ME4
Drugs

What you can answer from here — as of September 07, 2019

10DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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47+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Melatonin receptor type 1A, how selective are they, and which programs against it are still in active trials?

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