Glucagon receptor

BE0000527ProteinHumansGCGR

G protein-coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. It is acted on by 19 drugs in DrugBank.

Gene name
GCGR
UniProtKB entry
P47871Swiss-Prot
Cellular location
Cell membrane
Residues / weight
477 residues · 54,008 Da
Also known as
GL-R

Resolves to

Protein
UniProtP47871UniProt nameGLR_HUMAN
Gene
HGNCHGNC:4192NCBI Gene2642GenBank439690GeneCardsGCGR
Pharmacology
IUPHAR/GtoPdb251KEGGhsa:2642
Structure
PDB2A83PDB3CZFPDB4ERS
Drugs

What you can answer from here — as of September 07, 2019

19DrugsApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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63+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Glucagon receptor, how selective are they, and which programs against it are still in active trials?

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