Progesterone receptor

BE0000557ProteinHumansPGR

The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. It is acted on by 65 drugs in DrugBank.

Gene name
PGR
UniProtKB entry
P06401Swiss-Prot
Cellular location
Nucleus
Residues / weight
933 residues · 98,980 Da
Also known as
NR3C3 · Nuclear receptor subfamily 3 group C member 3 · PR

Resolves to

Protein
UniProtP06401UniProt namePRGR_HUMAN
Gene
HGNCHGNC:8910NCBI Gene5241GenBank35652GeneCardsPGR
Pharmacology
IUPHAR/GtoPdb627KEGGhsa:5241
Structure
PDB1A28PDB1E3KPDB1SQN
Drugs

What you can answer from here — as of September 07, 2019

65DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
94Clinical trialsTrials of drugs acting on it, by phase and status
Sign in
19GO termsFunction, process and component, as structured annotations
Sign in
3Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
261+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Progesterone receptor, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In