Cationic amino acid transporter 2

BE0000562ProteinHumansSLC7A2

Functions as a permease involved in the transport of the cationic amino acids (L-arginine, L-lysine, L-ornithine and L-homoarginine); the affinity for its substrates differs between isoforms created by alternative splicing (PubMed:28684763, PubMed:9174363). It is acted on by 3 drugs in DrugBank.

Gene name
SLC7A2
UniProtKB entry
P52569Swiss-Prot
Cellular location
Cell membrane
Residues / weight
658 residues · 71,672 Da
Also known as
ATRC2 · CAT-2 · CAT2 · Low affinity cationic amino acid transporter 2 · Solute carrier family 7 member 2

Resolves to

Protein
UniProtP52569UniProt nameCTR2_HUMAN
Gene
HGNCHGNC:11060NCBI Gene6542GenBank849051GeneCardsSLC7A2
Pharmacology
KEGGhsa:6542
Drugs

What you can answer from here — as of September 03, 2024

3DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
11GO termsFunction, process and component, as structured annotations
Sign in
2Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
15+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Cationic amino acid transporter 2, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In