Spermine oxidase

BE0000566ProteinHumansSMOX

Flavoenzyme which catalyzes the oxidation of spermine to spermidine. It is acted on by 3 drugs in DrugBank.

Gene name
SMOX
UniProtKB entry
Q9NWM0Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
555 residues · 61,819 Da
Also known as
1.5.3.16 · C20orf16 · PAO-1 · PAOh1 · Polyamine oxidase 1

Resolves to

Protein
UniProtQ9NWM0UniProt nameSMOX_HUMAN
Gene
HGNCHGNC:15862NCBI Gene54498GenBank14860862GeneCardsSMOX
Pharmacology
KEGGhsa:54498
Structure
PDB7OXLPDB7OY0
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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20+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Spermine oxidase, and which indications are they being tested in?

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