NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9

BE0000596ProteinHumansNDUFB9

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. It is acted on by 1 drug in DrugBank.

Gene name
NDUFB9
UniProtKB entry
Q9Y6M9Swiss-Prot
Cellular location
Mitochondrion inner membrane
Residues / weight
179 residues · 21,831 Da
Also known as
CI-B22 · Complex I-B22 · LYR motif-containing protein 3 · LYRM3 · NADH-ubiquinone oxidoreductase B22 subunit

Resolves to

Protein
UniProtQ9Y6M9UniProt nameNDUB9_HUMAN
Gene
HGNCHGNC:7704NCBI Gene4715GenBank5326828GeneCardsNDUFB9
Pharmacology
KEGGhsa:4715
Structure
PDB5XTCPDB5XTDPDB5XTH
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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12+ReferencesStructured and connected to the statements they support
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Which approved drugs act on NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9, how selective are they, and which programs against it are still in active trials?

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