Aldehyde dehydrogenase family 3 member A2

BE0000600ProteinHumansALDH3A2

Catalyzes the oxidation of medium and long chain aliphatic aldehydes to fatty acids. It is acted on by 6 drugs in DrugBank.

Gene name
ALDH3A2
UniProtKB entry
P51648Swiss-Prot
Cellular location
Microsome membrane
Residues / weight
485 residues · 54,847 Da
Also known as
1.2.1.3 · 1.2.1.94 · Aldehyde dehydrogenase 10 · ALDH10 · FALDH

Resolves to

Protein
UniProtP51648UniProt nameAL3A2_HUMAN
Gene
HGNCHGNC:403NCBI Gene224GenBank1082036GeneCardsALDH3A2
Pharmacology
KEGGhsa:224
Structure
PDB4QGK
Drugs

What you can answer from here — as of September 03, 2024

6DrugsApproved to experimental, with action, bond type and pharmacological action
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10GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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20+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Aldehyde dehydrogenase family 3 member A2, how selective are they, and which programs against it are still in active trials?

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