3',5'-cyclic-AMP phosphodiesterase 7B

BE0000627ProteinHumansPDE7B

Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes (PubMed:10814504, PubMed:10872825).

Gene name
PDE7B
UniProtKB entry
Q9NP56Swiss-Prot
Residues / weight
450 residues · 51,835 Da
Also known as
3.1.4.53 · cAMP-specific phosphodiesterase 7B

Resolves to

Protein
UniProtQ9NP56UniProt namePDE7B_HUMAN
Gene
HGNCHGNC:8792NCBI Gene27115GenBank8439497GeneCardsPDE7B
Pharmacology
IUPHAR/GtoPdb1306KEGGhsa:27115

What you can answer from here — as of September 03, 2024

1Metabolic reactionDrug transformations it catalyses, substrate to product
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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5+ReferencesStructured and connected to the statements they support
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Which compounds in development act on 3',5'-cyclic-AMP phosphodiesterase 7B, and which indications are they being tested in?

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