Phosphatidylserine decarboxylase proenzyme, mitochondrial

BE0000673ProteinHumansPISD

Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) (PubMed:30488656, PubMed:30858161). It is acted on by 1 drug in DrugBank.

Gene name
PISD
UniProtKB entry
Q9UG56Swiss-Prot
Cellular location
Mitochondrion inner membrane
Residues / weight
409 residues · 46,671 Da
Also known as
4.1.1.65

Resolves to

Protein
UniProtQ9UG56UniProt namePISD_HUMAN
Gene
HGNCHGNC:8999NCBI Gene23761GenBank57997016GeneCardsPISD
Pharmacology
KEGGhsa:23761
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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9+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Phosphatidylserine decarboxylase proenzyme, mitochondrial, how selective are they, and which programs against it are still in active trials?

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