NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial

BE0000676ProteinHumansNDUFB8

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. It is acted on by 1 drug in DrugBank.

Gene name
NDUFB8
UniProtKB entry
O95169Swiss-Prot
Cellular location
Mitochondrion inner membrane
Residues / weight
186 residues · 21,766 Da
Also known as
CI-ASHI · Complex I-ASHI · NADH-ubiquinone oxidoreductase ASHI subunit

Resolves to

Protein
UniProtO95169UniProt nameNDUB8_HUMAN
Gene
HGNCHGNC:7703NCBI Gene4714GenBank4164448GeneCardsNDUFB8
Pharmacology
KEGGhsa:4714
Structure
PDB5XTCPDB5XTDPDB5XTH
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
5GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
11+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In