NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3

BE0000684ProteinHumansNDUFA3

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. It is acted on by 1 drug in DrugBank.

Gene name
NDUFA3
UniProtKB entry
O95167Swiss-Prot
Cellular location
Mitochondrion inner membrane
Residues / weight
84 residues · 9,279 Da
Also known as
CI-B9 · Complex I-B9 · NADH-ubiquinone oxidoreductase B9 subunit

Resolves to

Protein
UniProtO95167UniProt nameNDUA3_HUMAN
Gene
HGNCHGNC:7686NCBI Gene4696GenBank4164444GeneCardsNDUFA3
Pharmacology
KEGGhsa:4696
Structure
PDB5XTCPDB5XTDPDB5XTH
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which approved drugs act on NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3, how selective are they, and which programs against it are still in active trials?

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