Fibroblast growth factor 1

BE0000689ProteinHumansFGF1

Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. It is acted on by 15 drugs in DrugBank.

Gene name
FGF1
UniProtKB entry
P05230Swiss-Prot
Cellular location
Secreted
Residues / weight
155 residues · 17,460 Da
Also known as
Acidic fibroblast growth factor · aFGF · ECGF · Endothelial cell growth factor · FGF-1

Resolves to

Protein
UniProtP05230UniProt nameFGF1_HUMAN
Gene
HGNCHGNC:3665NCBI Gene2246GenBank181942GeneCardsFGF1
Pharmacology
KEGGhsa:2246
Structure
PDB1AXMPDB1DJSPDB1DZC
Drugs

What you can answer from here — as of September 07, 2019

15DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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14GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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69+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Fibroblast growth factor 1, how selective are they, and which programs against it are still in active trials?

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