ADP/ATP translocase 2

BE0000709ProteinHumansSLC25A5

ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell (By similarity). It is acted on by 2 drugs in DrugBank.

Gene name
SLC25A5
UniProtKB entry
P05141Swiss-Prot
Cellular location
Mitochondrion inner membrane
Residues / weight
298 residues · 32,852 Da
Also known as
AAC2 · Adenine nucleotide translocator 2 · ADP,ATP carrier protein 2 · ADP,ATP carrier protein, fibroblast isoform · ANT 2

Resolves to

Protein
UniProtP05141UniProt nameADT2_HUMAN
Gene
HGNCHGNC:10991NCBI Gene292GenBank178661GeneCardsSLC25A5
Pharmacology
KEGGhsa:292
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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16GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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20+ReferencesStructured and connected to the statements they support
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Which approved drugs act on ADP/ATP translocase 2, how selective are they, and which programs against it are still in active trials?

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