Retinol dehydrogenase 12

BE0000726ProteinHumansRDH12

Retinoids dehydrogenase/reductase with a clear preference for NADP. It is acted on by 1 drug in DrugBank.

Gene name
RDH12
UniProtKB entry
Q96NR8Swiss-Prot
Cellular location
Endoplasmic reticulum membrane
Residues / weight
316 residues · 35,093 Da
Also known as
1.1.1.300 · All-trans and 9-cis retinol dehydrogenase · SDR7C2 · Short chain dehydrogenase/reductase family 7C member 2

Resolves to

Protein
UniProtQ96NR8UniProt nameRDH12_HUMAN
Gene
HGNCHGNC:19977NCBI Gene145226GenBank16549449GeneCardsRDH12
Pharmacology
KEGGhsa:145226
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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13+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Retinol dehydrogenase 12, how selective are they, and which programs against it are still in active trials?

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