Glutathione S-transferase kappa 1

BE0000808ProteinHumansGSTK1

Glutathione S-transferase that catalyzes the conjugation of glutathione to exogenous and endogenous compounds (PubMed:14709161, PubMed:14742434). It is acted on by 2 drugs in DrugBank.

Gene name
GSTK1
UniProtKB entry
Q9Y2Q3Swiss-Prot
Cellular location
Peroxisome
Residues / weight
226 residues · 25,497 Da
Also known as
2.5.1.18 · Glutathione S-transferase subunit 13 · GST 13-13 · GST class-kappa · GSTK1-1

Resolves to

Protein
UniProtQ9Y2Q3UniProt nameGSTK1_HUMAN
Gene
HGNCHGNC:16906NCBI Gene373156GenBank41351794GeneCardsGSTK1
Pharmacology
KEGGhsa:373156
Structure
PDB1YZXPDB3RPNPDB3RPP
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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14+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Glutathione S-transferase kappa 1, how selective are they, and which programs against it are still in active trials?

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