Glutathione S-transferase Mu 4

BE0000812ProteinHumansGSTM4

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles (PubMed:8203914, PubMed:8373352). It is acted on by 6 drugs in DrugBank.

Gene name
GSTM4
UniProtKB entry
Q03013Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
218 residues · 25,561 Da
Also known as
2.5.1.18 · GST class-mu 4 · GST-Mu2 · GSTM4-4 · Leukotriene C4 synthase GSTM4

Resolves to

Protein
UniProtQ03013UniProt nameGSTM4_HUMAN
Gene
HGNCHGNC:4636NCBI Gene2948GenBank306819GeneCardsGSTM4
Pharmacology
KEGGhsa:2948
Structure
PDB4GTU
Drugs

What you can answer from here — as of September 07, 2019

6DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
8GO termsFunction, process and component, as structured annotations
Sign in
2Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
19+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Glutathione S-transferase Mu 4, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In