Receptor activity-modifying protein 3

BE0000861ProteinHumansRAMP3

Accessory protein that interacts with and modulates the function of G protein-coupled receptors including calcitonin gene-related peptide type 1 receptor (CALCRL), calcitonin receptor (CALCR) and G protein-coupled estrogen receptor 1 (GPER1) (PubMed:23674134, PubMed:9620797). It is acted on by 1 drug in DrugBank.

Gene name
RAMP3
UniProtKB entry
O60896Swiss-Prot
Cellular location
Cell membrane
Residues / weight
148 residues · 16,518 Da
Also known as
Calcitonin-receptor-like receptor activity-modifying protein 3 · CRLR activity-modifying protein 3

Resolves to

Protein
UniProtO60896UniProt nameRAMP3_HUMAN
Gene
HGNCHGNC:9845NCBI Gene10268GenBank3171914GeneCardsRAMP3
Pharmacology
IUPHAR/GtoPdb53KEGGhsa:10268
Structure
PDB6UUSPDB6UVAPDB7TZF
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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12GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Receptor activity-modifying protein 3, how selective are they, and which programs against it are still in active trials?

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