Islet amyloid polypeptide

BE0000921ProteinHumansIAPP

Amylin/IAPP is a glucoregulatory peptide hormone that plays an important role in the regulation of energy homeostasis (PubMed:2690069). It is acted on by 3 drugs in DrugBank.

Gene name
IAPP
UniProtKB entry
P10997Swiss-Prot
Cellular location
Secreted
Residues / weight
89 residues · 9,806 Da
Also known as
Amylin · DAP · Diabetes-associated peptide · IAPP · Insulinoma amyloid peptide

Resolves to

Protein
UniProtP10997UniProt nameIAPP_HUMAN
Gene
HGNCHGNC:5329NCBI Gene3375GenBank457131GeneCardsIAPP
Pharmacology
KEGGhsa:3375
Structure
PDB1KUWPDB2G48PDB2KB8
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
6GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
24+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Islet amyloid polypeptide, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In