Apolipoprotein A-II

BE0000922ProteinHumansAPOA2

May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism. It is acted on by 3 drugs in DrugBank.

Gene name
APOA2
UniProtKB entry
P02652Swiss-Prot
Cellular location
Secreted
Residues / weight
100 residues · 11,175 Da
Also known as
Apo-AII · ApoA-II · Apolipoprotein A2

Resolves to

Protein
UniProtP02652UniProt nameAPOA2_HUMAN
Gene
HGNCHGNC:601NCBI Gene336GenBank28748GeneCardsAPOA2
Pharmacology
KEGGhsa:336
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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44GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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28+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Apolipoprotein A-II, how selective are they, and which programs against it are still in active trials?

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