Complement decay-accelerating factor

BE0000929ProteinHumansCD55

This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. It is acted on by 2 drugs in DrugBank.

Gene name
CD55
UniProtKB entry
P08174Swiss-Prot
Cellular location
Cell membrane
Residues / weight
381 residues · 41,400 Da
Also known as
CR · DAF

Resolves to

Protein
UniProtP08174UniProt nameDAF_HUMAN
Gene
HGNCHGNC:2665NCBI Gene1604GenBank181468GeneCardsCD55
Pharmacology
KEGGhsa:1604
Structure
PDB1H03PDB1H04PDB1H2P
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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6Clinical trialsTrials of drugs acting on it, by phase and status
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14GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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33+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Complement decay-accelerating factor, how selective are they, and which programs against it are still in active trials?

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