Cytochrome b

BE0000938ProteinHumansMT-CYB

Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. It is acted on by 9 drugs in DrugBank.

Gene name
MT-CYB
UniProtKB entry
P00156Swiss-Prot
Cellular location
Mitochondrion inner membrane
Residues / weight
380 residues · 42,717 Da
Also known as
COB · Complex III subunit 3 · Complex III subunit III · CYTB · Cytochrome b-c1 complex subunit 3

Resolves to

Protein
UniProtP00156UniProt nameCYB_HUMAN
Gene
HGNCHGNC:7427NCBI Gene4519GenBank13016GeneCardsMT-CYB
Pharmacology
KEGGhsa:4519
Structure
PDB5XTEPDB5XTHPDB5XTI
Drugs

What you can answer from here — as of September 07, 2019

9DrugsApproved to experimental, with action, bond type and pharmacological action
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1Metabolic reactionDrug transformations it catalyses, substrate to product
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3GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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32+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Cytochrome b, and which indications are they being tested in?

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