Bifunctional epoxide hydrolase 2

BE0000950ProteinHumansEPHX2

Bifunctional enzyme (PubMed:12574510). It is acted on by 11 drugs in DrugBank.

Gene name
EPHX2
UniProtKB entry
P34913Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
555 residues · 62,615 Da

Resolves to

Protein
UniProtP34913UniProt nameHYES_HUMAN
Gene
HGNCHGNC:3402NCBI Gene2053GenBank181395GeneCardsEPHX2
Pharmacology
IUPHAR/GtoPdb2970KEGGhsa:2053
Structure
PDB1S8OPDB1VJ5PDB1ZD2
Drugs

What you can answer from here — as of September 07, 2019

11DrugsApproved to experimental, with action, bond type and pharmacological action
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16GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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55+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Bifunctional epoxide hydrolase 2, and which indications are they being tested in?

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