Histamine H3 receptor

BE0000968ProteinHumansHRH3

The H3 subclass of histamine receptors could mediate the histamine signals in CNS and peripheral nervous system. It is acted on by 24 drugs in DrugBank.

Gene name
HRH3
UniProtKB entry
Q9Y5N1Swiss-Prot
Cellular location
Cell membrane
Residues / weight
445 residues · 48,671 Da
Also known as
G protein-coupled receptor 97 · GPCR97 · H3R · HH3R

Resolves to

Protein
UniProtQ9Y5N1UniProt nameHRH3_HUMAN
Gene
HGNCHGNC:5184NCBI Gene11255GenBank5031291GeneCardsHRH3
Pharmacology
IUPHAR/GtoPdb264KEGGhsa:11255
Structure
PDB7F61PDB8YN5PDB8YN6
Drugs

What you can answer from here — as of September 07, 2019

24DrugsApproved to experimental, with action, bond type and pharmacological action
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3Clinical trialsTrials of drugs acting on it, by phase and status
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8GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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103+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Histamine H3 receptor, how selective are they, and which programs against it are still in active trials?

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