Cytochrome b-c1 complex subunit 1, mitochondrial

BE0001005ProteinHumansUQCRC1

Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. It is acted on by 9 drugs in DrugBank.

Gene name
UQCRC1
UniProtKB entry
P31930Swiss-Prot
Cellular location
Mitochondrion inner membrane
Residues / weight
480 residues · 52,645 Da
Also known as
Complex III subunit 1 · Core protein I · Ubiquinol-cytochrome-c reductase complex core protein 1

Resolves to

Protein
UniProtP31930UniProt nameQCR1_HUMAN
Gene
HGNCHGNC:12585NCBI Gene7384GenBank515634GeneCardsUQCRC1
Pharmacology
KEGGhsa:7384
Structure
PDB5XTEPDB5XTHPDB5XTI
Drugs

What you can answer from here — as of September 07, 2019

9DrugsApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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22+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Cytochrome b-c1 complex subunit 1, mitochondrial, and which indications are they being tested in?

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