CD40 ligand

BE0001006ProteinHumansCD40LG

Cytokine that acts as a ligand to CD40/TNFRSF5 (PubMed:1280226, PubMed:31331973). It is acted on by 10 drugs in DrugBank.

Gene name
CD40LG
UniProtKB entry
P29965Swiss-Prot
Cellular location
Cell membrane
Residues / weight
261 residues · 29,273 Da
Also known as
CD40-L · CD40L · T-cell antigen Gp39 · TNF-related activation protein · TNFSF5

Resolves to

Protein
UniProtP29965UniProt nameCD40L_HUMAN
Gene
HGNCHGNC:11935NCBI Gene959GenBank37270GeneCardsCD40LG
Pharmacology
KEGGhsa:959
Structure
PDB1ALYPDB1I9RPDB3LKJ
Drugs

What you can answer from here — as of September 07, 2019

10DrugsApproved to experimental, with action, bond type and pharmacological action
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17Clinical trialsTrials of drugs acting on it, by phase and status
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16GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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46+ReferencesStructured and connected to the statements they support
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Which compounds in development act on CD40 ligand, and which indications are they being tested in?

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