Corticotropin-releasing hormone

BE0001026ProteinHumansCRH

Hormone that plays a central role in whole body adaptation to stress (By similarity). It is acted on by 3 drugs in DrugBank.

Gene name
CRH
UniProtKB entry
P06850Swiss-Prot
Cellular location
Secreted
Residues / weight
196 residues · 21,422 Da
Also known as
Corticoliberin · Corticotropin-releasing factor · CRF

Resolves to

Protein
UniProtP06850UniProt nameCRH_HUMAN
Gene
HGNCHGNC:2355NCBI Gene1392GenBank35356GeneCardsCRH
Pharmacology
KEGGhsa:1392
Structure
PDB1GO9PDB1GOEPDB3EHT
Drugs

What you can answer from here — as of June 19, 2026

3DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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11GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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14+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Corticotropin-releasing hormone, how selective are they, and which programs against it are still in active trials?

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