Neutrophil gelatinase-associated lipocalin

BE0001084ProteinHumansLCN2

Iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development (PubMed:12453413, PubMed:20581821, PubMed:27780864). It is acted on by 6 drugs in DrugBank.

Gene name
LCN2
UniProtKB entry
P80188Swiss-Prot
Cellular location
Secreted
Residues / weight
198 residues · 22,588 Da
Also known as
25 kDa alpha-2-microglobulin-related subunit of MMP-9 · HNL · Lipocalin-2 · NGAL · Oncogene 24p3

Resolves to

Protein
UniProtP80188UniProt nameNGAL_HUMAN
Gene
HGNCHGNC:6526NCBI Gene3934GenBank929657GeneCardsLCN2
Pharmacology
KEGGhsa:3934
Structure
PDB1DFVPDB1L6MPDB1NGL
Drugs

What you can answer from here — as of September 07, 2019

6DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
5Clinical trialsTrials of drugs acting on it, by phase and status
Sign in
8GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
28+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Neutrophil gelatinase-associated lipocalin, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In