Calcitonin gene-related peptide 1

BE0001103ProteinHumansCALCA

CGRP1/CALCA is a peptide hormone that induces vasodilation mediated by the CALCRL-RAMP1 receptor complex (PubMed:1318039, PubMed:33602864, PubMed:9620797). It is acted on by 5 drugs in DrugBank.

Gene name
CALCA
UniProtKB entry
P06881Swiss-Prot
Cellular location
Secreted
Residues / weight
128 residues · 13,899 Da
Also known as
Alpha-type CGRP · CALC1 · Calcitonin gene-related peptide I · CGRP-I · CGRP1

Resolves to

Protein
UniProtP06881UniProt nameCALCA_HUMAN
Gene
HGNCHGNC:1437NCBI Gene796GenBank179828GeneCardsCALCA
Structure
PDB6E3YPDB7KNUPDB9AUC
Drugs

What you can answer from here — as of September 07, 2019

5DrugsApproved to experimental, with action, bond type and pharmacological action
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2Clinical trialsTrials of drugs acting on it, by phase and status
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11GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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20+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Calcitonin gene-related peptide 1, how selective are they, and which programs against it are still in active trials?

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