Thrombomodulin

BE0001151ProteinHumansTHBD

Endothelial cell receptor that plays a critical role in regulating several physiological processes including hemostasis, coagulation, fibrinolysis, inflammation, and angiogenesis (PubMed:10761923). It is acted on by 3 drugs in DrugBank.

Gene name
THBD
UniProtKB entry
P07204Swiss-Prot
Cellular location
Membrane
Residues / weight
575 residues · 60,329 Da
Also known as
Fetomodulin · THRM · TM

Resolves to

Protein
UniProtP07204UniProt nameTRBM_HUMAN
Gene
HGNCHGNC:11784NCBI Gene7056GenBank736251GeneCardsTHBD
Pharmacology
KEGGhsa:7056
Structure
PDB1ADXPDB1DQBPDB1DX5
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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3Clinical trialsTrials of drugs acting on it, by phase and status
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6GO termsFunction, process and component, as structured annotations
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6Pfam domainsDomain architecture mapped to Pfam families and clans
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28+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Thrombomodulin, how selective are they, and which programs against it are still in active trials?

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